Laboratory for Stem Cell and Retinal Regeneration, Division of Ophthalmic Genetics, The Eye Hospital of Wenzhou Medical University
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Short biography

Dr. Deng Pan is currently a research scientist in Jin’s lab. She moved to this lab in 2016 from Huazhong University of Science and Technology in Wuhan, where she obtained her Ph.D.

Through good basic knowledge in Biomedical Engineering, Dr. Deng Pan graduated cum laude from Huazhong University of Science and Technology in 2008. Then she entered into Britton Chance Center for Biomedical Photonics for a doctorate. During that time, she tried to label endogenous protein in living cells using designed organic fluorescent probes and attempted for the following live-cell imaging. By this way, she resolved F-actin and lysosome in living cells with well temporal resolution at the nano-scale by photoactivated localization microscopy (i.e., PALM), a single molecule super-resolution imaging technique.

Research interests

Dr. Deng Pan is interested in the morphological changes of mitochondria in photoreceptor during retina degeneration by designed fluorescent probes as well as other live-cell labeling approaches. She also has a strong interest in label-free quantitative imaging and analysis of the eye during retinopathy by nonlinear optical microscopy techniques, including two-photon excitation fluorescence (i.e., TPEF) and second-harmonic generation (i.e., SHG).

Selected publications

1. Pan, D#, Hu, Z#, Qiu, F#, Huang, Z., Ma, Y., Wang, Y., Qin, L., Zhang, Z., Zeng, S., Zhang, Y*. A general strategy for developing cell-permeable photo-modulatable organic fluorescent probes for live-cell super-resolution imaging. Nature Communications, 2014; 5: 5573. IF= 11.329, TOP期刊 1区


Hobby

Singing.


Laboratory for Stem Cell and Retinal Regeneration,
Division of Ophthalmic Genetics, The Eye Hospital
of Wenzhou Medical University, The State Key
Laboratory of Vision Science, China.
add.: No 270, West Xueyuan Rd., Wenzhou, 325027 China.
Tel/Fax: 86-577-88067926;
E-mail: rp[at]mail.eye.ac.cn