Laboratory for Stem Cell and Retinal Regeneration, Division of Ophthalmic Genetics, The Eye Hospital of Wenzhou Medical University
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Short biography

Dr. Qiang Lin received his B.S. degree in biological science from Wenzhou Medical College in 2011 and Ph.D from Kunming Institute of Zoology, Chinese Academy of Science, The University of Chinese Academy of Sciences in 2017. Afterwards he joined the lab as a postdoctoral fellow. Previously as a doctoral candidate, Dr. Qiang Lin focused on the genetic mechanism of human brain evolution with his supervisor Prof. Bing Su. He had successfully constructed a transgenic monkey model of human-specific gene copy srGAP2C and uncovered the human-specific hypo-methylation of a key brain size regulator CENPJ during his graduate career. Meanwhile he tried to utilize the CRISPR/Cas9 to construct the humanize-Foxp2 replacement monkey models.

Research interests

1. Utilize the knock-out monkey model to uncover the mechanism underlie the retinal degeneration(RD) and the intervention treatment

2. The morphology changes in visual cortex due to retinal degeneration

3. Mechanisms underlie the formation of brain neural network

Selected publications

1. Lei Shi#, Qiang Lin#, and Bing Su. Human-Specific Hypo-methylation of CENPJ, a Key Brain Size Regulator. Mol. Biol. Evol. 2014 31: 594-604.
2. Lei Shi, Qiang Lin and Bing Su. Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates. BMC Evolutionary Biology 2015 15:127.
3. Lei Shi, Ming Li, Qiang Lin, Xuebin Qi and Bing Su. Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans. BMC Biology 2013 11:62.


Hobby

Basketball, Badminton, travel, historical novels.


Laboratory for Stem Cell and Retinal Regeneration,
Division of Ophthalmic Genetics, The Eye Hospital
of Wenzhou Medical University, The State Key
Laboratory of Vision Science, China.
add.: No 270, West Xueyuan Rd., Wenzhou, 325027 China.
Tel/Fax: 86-577-88067926;
E-mail: rp[at]mail.eye.ac.cn