Laboratory for Stem Cell and Retinal Regeneration, Division of Ophthalmic Genetics, The Eye Hospital of Wenzhou Medical University
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Short biography

Xue-Bi Cai got her bachelor’s degree from Wenzhou Medical University (WMU) in July, 2015. Then she continued her education as a graduate student in WMU and got her master’s degree in July, 2018. At the meantime, she finished working as a rotation doctor in the Affiliated Eye Hospital and successfully passed the examinations in the Resident Doctor Standard Training System. Now, she is studying for PhD program and playing a pivotal role for the collaboration between Jin Lab and the Laboratory for Oocyte and Embryo Development of Monash University in Melbourne.

Research directions

Her research interests focus on molecular genetics of ocular diseases, esp. retinitis pigmentosa and allied diseases.

Selected publications

1. Xiang L#, Chen XJ#, Wu KC, Zhang CJ, Zhou GH, Lv JN, Sun LF, Cheng FF, Cai XB, Jin ZB*. miR-183/96 plays a pivotal regulatory role in mouse photoreceptor maturation and maintenance. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6376-6381. IF=9.423, TOP期刊 1区

2. Rao FQ, Cai XB, Cheng FF, Cheng W, Fang XL, Li N, Huang XF, Li LH, Jin ZB*. Mutations in LRP5, FZD4, TSPAN12, NDP, ZNF408 or KIF11 genes account for 38.7% Chinese patients with familial exudative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2623-2629. IF= 3.427, TOP期刊 2区

3. Lin B#, Cai XB#, Zheng ZL, Huang XF, Liu XL, Qu J, Jin ZB*. Clinical and genetic analyses reveal novel pathogenic ABCA4 mutations in Stargardt disease families. Sci Rep. 2016 Oct 14;6:35414. IF=5.228, 2区

4. Cai XB#, Huang XF#, Tong Y, Lu QK*, Jin ZB*. Novel CHM mutations identified in Chinese families with Choroideremia. Sci Rep. 2016 Oct 14;6:35360. IF=5.228, 2区

5. Jin ZB*#, Wu J#, Huang XF, Feng CY, Cai XB, Mao JY, Xiang L, Wu KC, Xiao X, Kloss BA, Li Z, Liu Z, Huang S, Shen M, Cheng FF, Cheng XW, Zheng ZL, Chen X, Zhuang W, Zhang Q, Young TL, Xie T, Lu F*, Qu J*. Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4219-4224.1615970114. IF=9.423, TOP期刊 1区

6.Jin ZB, Li Z, Liu Z, Jiang Y, Cai XB, Wu J*. Identification of de novo germline mutations and causal genes for sporadic diseases using trio-based whole-exome/genome sequencing. Biological Reviews. 2017 Nov 20. doi: 10.1111/brv.12383. IF=11.625, TOP期刊 1区

Hobby

Dancing.


Laboratory for Stem Cell and Retinal Regeneration,
Division of Ophthalmic Genetics, The Eye Hospital
of Wenzhou Medical University, The State Key
Laboratory of Vision Science, China.
add.: No 270, West Xueyuan Rd., Wenzhou, 325027 China.
Tel/Fax: 86-577-88067926;
E-mail: rp[at]mail.eye.ac.cn